Health & Wellness
Medical topics, mental health, and wellbeing
340 episodes · Page 8 of 15
#3268: Why Strattera Works (or Fails) Depending on Your Liver
How one liver enzyme explains wildly different reactions to the same ADHD drug.
#3261: The Hidden Zoo of Drug Testing
Mice dominate headlines, but drug validation relies on dogs, pigs, ferrets, and macaques — each chosen for a specific human system.
#3260: How 10,000 Lever Presses Predict Addiction Risk
How rat breakpoints predict human abuse potential — and whether we can replace animal testing.
#3259: How 3 Rs Shape Lab Animal Ethics Today
The three Rs—Replacement, Reduction, Refinement—guide lab animal ethics. But do they go far enough?
#3255: Catatonia Beyond the Frozen Statue
Catatonia isn't just frozen stillness—it's a motor dysregulation syndrome more common in mania than schizophrenia.
#3254: When a Single Patient Changes Medicine: Case Reports That Matter
Why do doctors write case reports for free? And how have single-patient observations sparked drug approvals?
#3253: Nicotine Receptors & Bupropion: How an Antidepressant Blocks Smoking
How bupropion hijacks nicotinic receptors to cut smoking reward and withdrawal — and why these receptors aren't really "nicotine" receptors.
#3248: Why Isn't Modafinil Used More for ADHD?
Modafinil boosts wakefulness and dopamine. So why does it lose to stimulants for ADHD?
#3242: Where to Put White Noise Machines for ADHD Focus
Desk placement is wrong. Here's where to put white noise machines for actual sound masking that works.
#3239: Why the Brain Doesn't Fight Back Against Vyvanse
How SSRIs and Vyvanse trick the brain’s homeostatic machinery into healing instead of resisting.
#3233: The Case for Identical Socks
How buying 30 identical pairs of socks can save 130 hours of your life and eliminate a neurological tax.
#3204: The Expectation Cascade: How to Live Your Own Life
Bronnie Ware's deathbed research reveals the #1 regret: not living true to yourself. How to escape the expectation cascade.
#3201: Why Your Baby Isn't Bored in the Kitchen
That kitchen walk isn't boring your baby — it's a sensory masterclass. Here's what the neuroscience actually says.
#3197: Can You Prevent Sensory Processing Issues in Infants?
Genetic predisposition meets environmental intervention. What parents can do in the critical 6-18 month window.
#3196: What Your 11-Month-Old Actually Sees, Hears, and Feels
Why teething pain feels like "my whole head is wrong" — and what actually soothes a feverish baby.
#3195: How to Save Your Brain State Like Git Stash
A structural approach to deep work when parenting makes interruption inevitable.
#3168: 30 BLE Tags for $60: DIY ADHD Object Tracking
Stop losing your stuff. Build a self-hosted BLE tracker system for 30 items at 1/8 the cost of commercial trackers.
#3166: The Split in Insomnia Treatment: SOI vs SMI
Sleep-onset and sleep-maintenance insomnia have different biology, different drugs, and different treatments.
#3164: The Million-Dollar Cost of Avoiding an Invoice
Why your brain treats charging for work like a social threat — and the neurological research that explains it.
#3163: How to Learn Life Skills Without the Shame
Why millions of adults can't do laundry without Google — and the emerging market for shame-free skill coaching.
#3148: What Vaping Does to Your Lungs Beyond Nicotine
Formaldehyde, heavy metals, and popcorn lung — the real chemistry of vaping vs. smoking.
#3147: Third-Hand Smoke: What Lingers in Your Walls
How to detect hidden cigarette residue in rentals and why third-hand smoke persists for years.
#3146: Why Youth Smoking Is Rising in Israel
Global smoking is down, but youth rates in Israel are rising. Here’s why.
#3145: Where Indoor Smoking Is Still Legal in 2026
Indonesia, Germany, Japan, Egypt, and Russia — the surprising places where lighting up indoors is still allowed.