#psychopharmacology
77 episodes
#5474: Why Tardive Dyskinesia Becomes Permanent
One in five antipsychotic patients develops TD. Why does it stick around after the drug stops — and how much do newer drugs help?
#5462: Why Dopamine Blockers Stop Nausea (And Cause Fatigue)
Dopamine blockers stop nausea but cause brutal next-day fatigue. Why the same receptor does both — and what makes them risky long-term.
#5449: The Neurotic Jew: Where the Stereotype Came From
The anxious, overthinking Jewish personality — where did it actually come from? The answer isn't what you'd expect.
#5284: ADHD Meds, Border Rules, and Thank-You Gifts
Why is it so hard for adults with ADHD to fill a stimulant prescription — and is a thank-you gift to the pharmacist ethical?
#5258: Vyvanse, Alcohol Withdrawal, and the Titration Problem
A listener's water-titration experiment with Vyvanse leads to a bigger question: can medicine model neurotransmitter systems in real time?
#5200: Gray Rocking vs. the Info Diet: What to Actually Share
Gray rocking gets the attention, but the info diet — quietly censoring what you disclose — may be the sharper survival tool.
#5195: When Real Danger Silences Phobias
A year of war and housing crisis erased his cockroach phobia. The science says that's not as strange as it sounds.
#5186: Why the Last Milligrams Are the Hardest
Most drugs come in doses designed for stable use — not for the tiny steps safe withdrawal requires. Here's what's changing.
#5105: The 69% Rule: What Gottman Method Says About Recurring Fights
69% of couple conflicts are perpetual. Learn how the Gottman Method turns gridlocked fights into graceful dialogue.
#4974: When a Culture You've Never Lived In Feels Like Home
Why K-dramas, Japanese aesthetics, or Kazakhstan can feel more like home than your own culture.
#4728: Why Humans Love the Burn: Spicy Food and the Drive to Alter Consciousness
Why do humans love spicy food? The answer reveals something surprising about our relationship with altered states.
#4365: When ADHD Meds Cause Evening Depression
How to tell if your evening despair is a stimulant crash or actual depression — and what to do about it.
#4306: Bowen Family Systems & Narcissism
How Murray Bowen’s eight concepts explain narcissistic family dynamics beyond pop-psychology labels.
#4133: Can a Narcissistic CEO Be Diagnosed?
When Wall Street rewards what the DSM calls pathological, what are we actually diagnosing?
#4119: Guilt as a Feature: How Judaism Processes Failure
Is guilt a feature or a bug in religious systems? One tradition has a built-in protocol for processing failure.
#4118: When Thoughts Feel Like Facts: Ego-Syntonic Thinking Explained
Why some people can't see their own catastrophic thoughts as distortions — and what that means for therapy.
#4117: Understanding Egosyntonic: Why Explanations Fail with Personality Disorders
What if the person you're trying to reach literally can't see their own behavior? One word explains why.
#3759: Drug Interaction Alerts: Why Doctors Ignore 90% of Warnings
Why do doctors override 90% of drug interaction alerts? The gap between database warnings and clinical judgment, explained.
#3705: What Your Sexual Fantasies Actually Mean
The data on common fantasies is genuinely surprising — and reveals how fantasy functions as an amplifier, not a substitute.
#3702: The Silent Side Effect of SSRIs
60% of patients on SSRIs experience sexual dysfunction. We break down the why and what to do.
#3700: Splitting Vyvanse for a Smoother Curve
Can you split a Vyvanse dose for better focus? We break down the pharmacokinetics of lisdexamfetamine and water titration.
#3687: How Curiosity Shapes Specialists and Generalists
Why some brains crave novelty while others seek depth—and how both types fit together in society.
#3600: How Do We Heal Trauma at Societal Scale?
Exploring complex PTSD, treatment options from EMDR to MDMA, and how to scale healing beyond the therapist's office.
#3527: When SNRIs Beat SSRIs: Pain, Energy & ADHD
Why pick an SNRI when withdrawal is worse? The answer depends on pain, energy, attention, and which molecule we're talking about.